ritlecitinib standard substance (MedChemExpress)
Structured Review

Ritlecitinib Standard Substance, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ritlecitinib standard substance/product/MedChemExpress
Average 93 stars, based on 9 article reviews
Images
1) Product Images from "The Stability-Indicating Ultra High-Performance Liquid Chromatography with Diode Array Detector and Tandem Mass Spectrometry Method Applied for the Forced Degradation Study of Ritlecitinib: An Appraisal of Green and Blue Metrics"
Article Title: The Stability-Indicating Ultra High-Performance Liquid Chromatography with Diode Array Detector and Tandem Mass Spectrometry Method Applied for the Forced Degradation Study of Ritlecitinib: An Appraisal of Green and Blue Metrics
Journal: Pharmaceuticals
doi: 10.3390/ph18010124
Figure Legend Snippet: Structure of the irreversible Janus kinase 3 and tyrosine kinase inhibitor, ritlecitinib.
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Figure Legend Snippet: Summarized system suitability data of the newly developed stability-indicating method (ritlecitinib concentration level 10 µg/mL; n = 6).
Techniques Used: Concentration Assay
Figure Legend Snippet: Representative LC chromatograms of ritlecitinib samples (100 µg/mL): ( a ) control, ( b ) basic, and ( c ) oxidative degradation.
Techniques Used: Control
Figure Legend Snippet: Summarized forced degradation study data.
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Figure Legend Snippet: UHPLC-ESI-QQQ data of ritlecitinib and its degradation products.
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Figure Legend Snippet: Mass spectra data of ritlecitinib. ( a ) Full scan ESI-MS spectrum, showing the protonated molecular ion [M+H] + at m / z 286. ( b ) Product ion ESI-MS/MS spectrum of the protonated molecular ion [M+H] + ( m / z 286), collision energy of 20 V (insert: proposed fragmentation pattern).
Techniques Used: Tandem Mass Spectroscopy
Figure Legend Snippet: The MoGAPI score of ritlecitinib forced degradation protocol.
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Figure Legend Snippet: The ComplexGAPI score of ritlecitinib forced degradation protocol.
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Figure Legend Snippet: The AGREE score of ritlecitinib forced degradation protocol.
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Figure Legend Snippet: The AGREEprep score of ritlecitinib forced degradation protocol.
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Figure Legend Snippet: The BAGI score of ritlecitinib forced degradation protocol.
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